Nuevos biomaterialesestudio in vivo del carburo de silicio como material osteointegrador

  1. Jon Rodino Padín 1
  2. V. Castaño Montón 1
  3. Jacinto Pérez Borrajo 2
  4. Pío Manuel González Fernández 2
  5. Julia Serra Rodríguez 2
  6. F. M. Muñoz 3
  7. N. Miño 3
  1. 1 Hospital Xeral Cíes
  2. 2 Universidade de Vigo, Departamento de Física Aplicada
  3. 3 Universidade de Santiago de Compostela, Facultad de Veterinaria
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Journal:
Trauma

ISSN: 1888-6116

Year of publication: 2014

Volume: 25

Issue: 4

Pages: 232-236

Type: Article

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Abstract

Objective: To evaluate, using in vivo tests, the biocompatibility and the degree of bone penetration into the porous microstructure of silicon carbide (SiC). Material and methods: For this purpose cylindres of SiC obatained from wood of pine and sapeli were implanted in femoral condyles of rabbits. As reference material we used titanium cylinders. The slaughter of animals was performed at 12 weeks of implantation and proceeded to the histological examination of the samples. Results: We see a growth of bone trabeculae, both on the surface of the implant and through its porous structure, without signs of inflammation or appearance of fibrous tissue around the samples. These results are confirmed by scanning electron microscopy scanning (SEM) and X-ray analysis by dispersion of energies (EDS). Conclusion: Biomorphic silicon carbide (SiC) is a ceramic with excellent mechanical properties and interconnected porosity which gives a special attraction for their biomedical applications in orthopaedic implants

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