Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: Structure determination of both ternary complexes and implications for drug design

  1. Cousido-Siah, A.
  2. Ruiz, F.X.
  3. Mitschler, A.
  4. Porté, S.
  5. De Lera, A.R.
  6. Martín, M.J.
  7. Manzanaro, S.
  8. De La Fuente, J.A.
  9. Terwesten, F.
  10. Betz, M.
  11. Klebe, G.
  12. Farrés, J.
  13. Parés, X.
  14. Podjarny, A.
Revista:
Acta Crystallographica Section D: Biological Crystallography

ISSN: 0907-4449 1399-0047

Ano de publicación: 2014

Volume: 70

Número: 3

Páxinas: 889-903

Tipo: Artigo

DOI: 10.1107/S1399004713033452 GOOGLE SCHOLAR