Publicacións (30) Publicacións de MARTA DOMINGUEZ SEOANE

2021

  1. Synthetic Studies on Alotamide A: Construction of N-Demethylalotamide A

    European Journal of Organic Chemistry, Vol. 2021, Núm. 44, pp. 6057-6070

  2. Total Synthesis of Homo-and Heterodimeric Bispyrrolidinoindoline Dioxopiperazine Natural Products

    Journal of Natural Products, Vol. 84, Núm. 6, pp. 1725-1737

2020

  1. Synthesis of C11-to-C14 methyl-shifted all-: Trans -retinal analogues and their activities on human aldo-keto reductases

    Organic and Biomolecular Chemistry, Vol. 18, Núm. 25, pp. 4788-4801

2019

  1. Apo-14´-carotenoic acid is a novel endogenous and bioactive apo-carotenoid

    Nutrients, Vol. 11, Núm. 9

  2. Improved synthesis of key fragments for the preparation of natural product incednine

    Tetrahedron, Vol. 75, Núm. 43

2018

  1. Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases

    Tetrahedron, Vol. 74, Núm. 21, pp. 2567-2574

2015

  1. Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

    ChemMedChem, Vol. 10, Núm. 12, pp. 1989-2003

2013

  1. Aldo-keto reductases in retinoid metabolism: Search for substrate specificity and inhibitor selectivity

    Chemico-Biological Interactions

2012

  1. Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach

    PLoS ONE, Vol. 7, Núm. 8

  2. Stereocontrolled synthesis of (S)-9-cis-4-oxo-13,14-dihydroretinoic acid

    Tetrahedron, Vol. 68, Núm. 6, pp. 1756-1761

2011

  1. Design and evaluation of fragment-like estrogen receptor tetrahydroisoquinoline ligands from a scaffold-detection approach

    Journal of Medicinal Chemistry, Vol. 54, Núm. 7, pp. 2005-2011

  2. Synthesis of C40-symmetrical fully conjugated carotenoids by olefin metathesis

    European Journal of Organic Chemistry, pp. 6704-6712

2010

  1. Increased adiposity in the retinol saturase-knockout mouse

    FASEB Journal, Vol. 24, Núm. 4, pp. 1261-1270

2009

  1. Activation of retinoic acid receptors by dihydroretinoids

    Molecular Pharmacology, Vol. 76, Núm. 6, pp. 1228-1237

  2. Aldo-keto reductases from the AKR1B subfamily: Retinoid specificity and control of cellular retinoic acid levels

    Chemico-Biological Interactions, Vol. 178, Núm. 1-3, pp. 171-177

  3. Bioactivity-guided mapping and navigation of chemical space

    Nature Chemical Biology, Vol. 5, Núm. 8, pp. 585-592

  4. Complex thermal behavior of 11-cis-retinal, the ligand of the visual pigments

    Journal of Organic Chemistry, Vol. 74, Núm. 3, pp. 1007-1013

  5. Structural coupling of 11-cis-7-methyl-retinal and amino acids at the ligand binding pocket of rhodopsin

    Photochemistry and Photobiology

2008

  1. Stereospecificity of retinol saturase: Absolute configuration, synthesis, and biological evaluation of dihydroretinoids

    Journal of the American Chemical Society, Vol. 130, Núm. 4, pp. 1154-1155

2007

  1. Specificity of zebrafish retinol saturase: Formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol

    Biochemistry, Vol. 46, Núm. 7, pp. 1811-1820