CINBIO
Centro de investigación
MARTA
DOMINGUEZ SEOANE
TITULAR DE UNIVERSIDADE - TEMPO COMPLETO
Publicacións nas que colabora con MARTA DOMINGUEZ SEOANE (27)
2021
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Synthetic Studies on Alotamide A: Construction of N-Demethylalotamide A
European Journal of Organic Chemistry, Vol. 2021, Núm. 44, pp. 6057-6070
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Total Synthesis of Homo-and Heterodimeric Bispyrrolidinoindoline Dioxopiperazine Natural Products
Journal of Natural Products, Vol. 84, Núm. 6, pp. 1725-1737
2020
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Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines
RSC Medicinal Chemistry, Vol. 11, Núm. 10, pp. 1210-1225
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Synthesis of C11-to-C14 methyl-shifted all-: Trans -retinal analogues and their activities on human aldo-keto reductases
Organic and Biomolecular Chemistry, Vol. 18, Núm. 25, pp. 4788-4801
2019
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Apo-14´-carotenoic acid is a novel endogenous and bioactive apo-carotenoid
Nutrients, Vol. 11, Núm. 9
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Improved synthesis of key fragments for the preparation of natural product incednine
Tetrahedron, Vol. 75, Núm. 43
2018
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Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases
Tetrahedron, Vol. 74, Núm. 21, pp. 2567-2574
2015
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Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10
ChemMedChem, Vol. 10, Núm. 12, pp. 1989-2003
2013
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Aldo-keto reductases in retinoid metabolism: Search for substrate specificity and inhibitor selectivity
Chemico-Biological Interactions
2012
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Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach
PLoS ONE, Vol. 7, Núm. 8
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Stereocontrolled synthesis of (S)-9-cis-4-oxo-13,14-dihydroretinoic acid
Tetrahedron, Vol. 68, Núm. 6, pp. 1756-1761
2010
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Increased adiposity in the retinol saturase-knockout mouse
FASEB Journal, Vol. 24, Núm. 4, pp. 1261-1270
2009
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Activation of retinoic acid receptors by dihydroretinoids
Molecular Pharmacology, Vol. 76, Núm. 6, pp. 1228-1237
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Aldo-keto reductases from the AKR1B subfamily: Retinoid specificity and control of cellular retinoic acid levels
Chemico-Biological Interactions, Vol. 178, Núm. 1-3, pp. 171-177
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Complex thermal behavior of 11-cis-retinal, the ligand of the visual pigments
Journal of Organic Chemistry, Vol. 74, Núm. 3, pp. 1007-1013
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Structural coupling of 11-cis-7-methyl-retinal and amino acids at the ligand binding pocket of rhodopsin
Photochemistry and Photobiology
2008
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Stereospecificity of retinol saturase: Absolute configuration, synthesis, and biological evaluation of dihydroretinoids
Journal of the American Chemical Society, Vol. 130, Núm. 4, pp. 1154-1155
2007
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Specificity of zebrafish retinol saturase: Formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol
Biochemistry, Vol. 46, Núm. 7, pp. 1811-1820
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Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10
Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Núm. 52, pp. 20764-20769
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Total synthesis of peridinin and related C37-norcarotenoid butenolides
Chemistry - A European Journal, Vol. 13, Núm. 4, pp. 1273-1290