Difuncionalización selectiva de sistemas insaturados mediante catálise de cobre
- Pérez Saavedra, Borja
- Carlos Saa Rodríguez Zuzendaria
- Martin Fañanas Mastral Zuzendarikidea
Defentsa unibertsitatea: Universidade de Santiago de Compostela
Fecha de defensa: 2019(e)ko urria-(a)k 14
- Rosana Álvarez Rodríguez Presidentea
- José Pérez Sestelo Idazkaria
- Fernando José López García Kidea
Mota: Tesia
Laburpena
In this thesis, two selective multiple C–C bond functionalization strategies have been investigated. In the first part, a copper-catalysed carboarylation/cyclization of alkynyl phosphonates with diaryliodonium salts has been developed giving access to five and six membered ring cyclic enol phosphonates bearing tetrasubstituted double bonds in high yields under mild conditions. In the second part, a copper-catalysed tricomponent reaction between allenes, hydroxylamine esters and bis(pinacolato)diboron has been explored for the regio-, chemo- and diastereoselective synthesis of α- and β-aminoalkenylboronates in good yields.