Publicacións en colaboración con investigadores/as de Universitat Autònoma de Barcelona (17)

2020

  1. Synthesis of C11-to-C14 methyl-shifted all-: Trans -retinal analogues and their activities on human aldo-keto reductases

    Organic and Biomolecular Chemistry, Vol. 18, Núm. 25, pp. 4788-4801

2018

  1. Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases

    Tetrahedron, Vol. 74, Núm. 21, pp. 2567-2574

2017

  1. Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008

    Chemico-Biological Interactions, Vol. 276, pp. 174-181

2015

  1. Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

    ChemMedChem, Vol. 10, Núm. 12, pp. 1989-2003

2014

  1. Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: Structure determination of both ternary complexes and implications for drug design

    Acta Crystallographica Section D: Biological Crystallography, Vol. 70, Núm. 3, pp. 889-903

2013

  1. Aldo-keto reductases in retinoid metabolism: Search for substrate specificity and inhibitor selectivity

    Chemico-Biological Interactions

2012

  1. Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach

    PLoS ONE, Vol. 7, Núm. 8

2009

  1. Aldo-keto reductases from the AKR1B subfamily: Retinoid specificity and control of cellular retinoic acid levels

    Chemico-Biological Interactions, Vol. 178, Núm. 1-3, pp. 171-177

  2. C-C reductive elimination in palladium complexes, and the role of coupling additives. A DFT study supported by experiment

    Journal of the American Chemical Society, Vol. 131, Núm. 10, pp. 3650-3657

2007

  1. Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Núm. 52, pp. 20764-20769

2006

  1. Synthesis of enantiopure C3- and C4-hydroxyretinals and their enzymatic reduction by ADH8 from Xenopus laevis

    Organic and Biomolecular Chemistry, Vol. 4, Núm. 1, pp. 155-164

2005

  1. Synthesis of N-heteroaryl retinals and their artificial bacteriorhodopsins

    ChemBioChem, Vol. 6, Núm. 11, pp. 2078-2087

2004

  1. Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: Effect of Tween 80

    Archives of Biochemistry and Biophysics

  2. Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1)

    Organic and Biomolecular Chemistry, Vol. 2, Núm. 22, pp. 3368-3373

  3. The specificity of alcohol dehydrogenase with cis-retinoids Activity with 11-cis-retinol and localization in retina

    European Journal of Biochemistry, Vol. 271, Núm. 9, pp. 1660-1670

1995

  1. Experimental and Theoretical Analysis of the Steric Tolerance of the Binding Site of Bacterioopsin with the Use of Side-Chain Methyl-Shifted Retinal Analogs

    Journal of the American Chemical Society, Vol. 117, Núm. 31, pp. 8220-8231

  2. Fourier transform infrared spectroscopy indicates a major conformational rearrangement in the activation of rhodopsin

    Biophysical Journal, Vol. 69, Núm. 3, pp. 1077-1082